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"Beneath The Skin" by Ceclia Condit combines true crime and art in an unforgettable way – Boing Boing11.30.21

BENEATH THE SKIN (1981) by Cecelia Condit explores the grim side of female subjectivity as it merges a true crime story about an unsolved murder with personal nightmare imagery. The film has a hallucinatory quality to it, and is as beautiful as it is unsettling. I'm fascinated by all of the contrasting elements of this film, such as the relationship between light and dark, impersonal and personal, and dream vs. reality. This 11 minute film is the first notable work by Condit, who's gone on to make many more compelling videos since.

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Relating a tale told by a girl on a swing, Beneath the Skin explores the contrast between the impersonal horror of a news story heard on television and the involvement of the storyteller in a nightmare, which gradually becomes more familiar and commonplace as the tale unfolds. The straightforward approach of the teller is humorously or frighteningly contrasted by a bombardment of visual images which mock or intensify the macabre flavor of the work.

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Yellowstone Recap: You Cant Wash Lonely Off – Vulture11.30.21


Under a Blanket of Red

Season 4 Episode 5

Editors Rating 2 stars **

Photo: Cam McLeod/Paramount

Last week, I wrote about Yellowstones tendency to cram half a dozen stories into one episode. That technique can work well if the stories are satisfying and complete, as in Winning or Learning. But Under a Blanket of Red is an even more scattered episode of Yellowstone than usual, one that introduces a number of new character stories but cant commit to following through on any of them. Its a paradox: Almost nothing seems to happen in this episode, and yet it still feels like its doing too much.

Take John Dutton, our ostensible protagonist, whose reclusiveness following the attempt on his life has suggested an interesting internal conflict for him this season. One son is dead, another he hasnt talked to in months, and now the third is spending time away from the ranch. With Kayce and his family back on the reservation, John no longer has enough distractions to keep his loneliness at bay; if Beths filthy suggestion last week was any hint, this is the time for John to consider whether he always wants to sleep alone.

Enter Summer Higgins, a protester at the Montana Livestock Association who takes issue with the state-sponsored police force that protects industrialized animal farming and the mass murder of millions of animals every year. So far, Summer is a character straight from the Taylor Sheridan playbook: generically liberal, needlessly aggressive, and out of touch, with no consistent political agenda besides defeating the rich old white man and his way of life. John relishes pointing out to her that no matter how ethical she thinks her diet is, animals were killed in making her food. He suggests that snakes, mice, and worms killed in field-plowing arent any different from slaughtering cattle; Summers just sensitive to how cute the animals are.

He has her arrested (completely by the book, as the sheriff clarifies), then later pays her bail and offers her a tour of the ranch, clearly coming from a place of loneliness. Their drive, at least, allows for some nuance: John proves to Summer that he does see the way the world is, acknowledging that there will come a time when Earth sheds us like dead skin, and it will be our own fault.

Thats about it so far, though, so if Summer is being positioned as a love interest for John, it might take a while. At this point, John has taught Summer more about his way of life than shes taught him about hers. Im curious if hell eventually come around to her thinking in any regard or if hell remain entrenched in his beliefs the way he has for most of the show.

But as is so often the case in Yellowstone, everything happens slowly except when Sheridan is itchy for some movement. We see Tate smiling and eating again after a few days in the sweat lodge; Monica finds a nice house in Pryor so she and Kayce can live without a father on either side hanging around all the time; and Beth drives to Salt Lake City just to look Bob in the eye when she fires him. (Caroline Warner acquiesced to her demand for controlling interest in Schwartz & Meyer offscreen, so Beth has taken the job at Market Equities.)

The most consequential plot movement in Under a Blanket of Red happens in Jamies story. As Kayce requested, he meets with Terrell Riggins, the man who set up the Dutton hits from prison. Jamie offers him immunity in exchange for intel, and Riggins seems to confirm the obvious: Garrett Randall, Jamies biological father, was behind the whole thing. (What are the chances Riggins winds up murdered in prison sometime soon and Jamie helps cover it up?)

But when Jamie gets back to Garretts house, hes ambushed before he can confront him. Yep, folks, its the long-delayed return of Christina, Jamies assistantlove interest whom we last saw in season two, demanding he get his priorities straight if he wanted to be part of his sons life. She is pleased with his new job and estrangement from John, but once again, well have to wait longer to see what this means in the grand scheme of things and to get a clear read on Garrett.

The saving grace, as is so often the case in this show, is the details. The warmth in Johns relationships with Kayce and Beth has been one of the nicest parts of the past couple seasons. I enjoy his frank discussion with Beth about the impossibility of finding solace and the necessity of seeing the world as it is. Later, when John mentions hes struggling with his conscience, Beth drops a funny gem: Id offer advice, Dad, but Ive never been in that situation.

And even though the scenes at the Four Sixes Ranch feel like a different show (because eventually they will be), there are some lovely moments there. Friendly Texan cowboy Ross (Barry Corbin) has a revealing conversation with Jimmy, explaining that ranching is art without an audience until the day you die. And then after youre dead, you dont have an audience either. And Jimmy later meets the real-life horse-training legend Buster Welch without realizing it.

These isolated moments and low-key stories have their charms, even without a greater purpose. But were now halfway through the fourth season of Yellowstone, and its hard to feel much momentum. Im okay with tuning in each week to watch some short stories play out, but Under a Blanket of Red feels like reading just the first few pages.

Rip is really holding a grudge about the fight Lloyd started with Walker, but to be fair, Lloyds still being a baby about it. I thought his final moment in the last episode was a breakthrough, but in this episode, hes back to staring down Walker, even watching as he and Laramie have sex outside. I do like the nice camaraderie hes developing with Carter, though.

Does anybody else keep thinking weve seen Jimmy for the last time on this show? I totally thought the final scene of the last episode was his final scene on this show. What exactly is this plot setting up for the spinoff, and what could make a better (temporary) ending for Jimmy than last week?

Keep up with all the drama of your favorite shows!

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Visual Arts graduates featured in upcoming exhibition The Brock News – Brock University11.30.21

A new exhibition will see the return of two Brock University graduates showcasing their artwork and creative research in the space where they once studied.

Beneath the Skin runs from Tuesday, Nov. 30 to Saturday, Dec. 18 featuring participating artists and Studio Art graduates Rea Kelly (BA 21) and Angelina Turner (BA 21). The opening reception will be held Thursday, Dec. 9 from 5 to 8 p.m. at the Visual Arts Gallery and Student Exhibition Space at the Marilyn I. Walker School of Fine and Performing Arts (MIWSFPA).

The exhibition examines themes related to human anatomy and the psyche with the intention of encouraging audiences to delve deeper into their physical and emotional identities.

The theme of my work is rooted in challenging the viewers perception of how portraits, and even selfies as an extension, are typically used to understand an outward appearance, status and social identity, said Kelly. Instead, my work focuses on the internal lived experience.

Turner said she took images of anatomy and intertwined them with other natural organisms to highlight the concept of interdependence in the world.

Many members of society, especially since the rise of smart technology, speak to feelings of loneliness and isolation, she said. But we arent alone, and I hope through my work I can show that to viewers.

The Visual Arts Gallery and Student Exhibition Space is located on the first floor of the MIWSFPA at 15 Artists Common in downtown St. Catharines. The gallery is open to the Brock community and wider public Tuesday to Saturday from 1 to 5 p.m. (September through April).

Brock students and staff are encouraged to RSVP through ExperienceBU to attend the exhibition and opening reception. All Brock University protocols apply including mandatory full COVID-19 vaccination and masks for all visitors. Community visitors are asked to enter the building through the main entrance for check-in at the Security desk.

Questions can be directed to the Visual Arts Gallery at

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Theyre Just Really, Really Absurd: Watch Sculptor Jes Fan Make Art With Testosterone and Melanin to Challenge Our Assumptions About Identity – artnet…11.30.21

Jes Fans media of choice might make other people squirm. Instead of paint or clay, Fan makes art with E. coli, semen, melanin, testosterone, blood, and urine.

After developing some of these culturally loaded materials in a lab with the help of scientists, Fan transforms them into sculptures with glossy finishes and near-erotic shapes. The result walks the line between beauty, absurdity, and the grotesque. And for Fan, thats the point.

A lot what Im trying to do with what we consider as gendered materials, or racialized materials, theyre just really, really absurd, the artist said in a 2020 interview for Art21s New York Close Up series. I was thinking a lot about how race, especially in the U.S., is seen as infectious. Think about China and coronavirus. Think about SARS and being in Hong Kong. And think about Jim Crow era, not sharing bodies of water. That idea of it being infected.

Production still from the Art21 New York Close Up film, Jes Fan: Infectious Beauty. Art21, Inc. 2020.

By injecting decaying biological matter into smooth, bulbous forms, Fan hopes to challenge viewers to examine closely held assumptions about what our culture values and what it rejects. That eroticness seduces you, Fan says. Its beauty in the gloss, and the possibility to see your own reflection in it. At the same time, youre actually staring at something that repulses you, that actually is considered infectious or unclean.

The artist, who was born in Canada, raised in Hong Kong, and now lives in Brooklyn, tackles these same themes in a video included in the New Museum Triennial, Soft Water Hard Stone, on view at the New York museum through January 23, 2022. Xenophoria (201820) chronicles Fans pursuit of eumelanin pigment, the molecule responsible for skin color.

As Fan dissects squid, harvests fungi, and locates moles in the film, the artist underscores the absurdity of the fetishization of a molecule that has caused centuries of racial discrimination, showing how it exists within all of us.

Watch the video, which originally appeared as part of Art21s New York Close Up series, below. Soft Water Hard Stone is on view at the New Museum in New York through January 23, 2022.

This is an installment of Art on Video, a collaboration between Artnet News and Art21 that brings you clips of newsmaking artists. A new series of the nonprofit Art21s flagship series Art in the Twenty-First Century is available now on PBS. Catch all episodes of other series like New York Close Up and Extended Play and learn about the organizations educational programs

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Definition, Causes, Risk Factors and Treatment for Skin Tags – WFMZ Allentown11.30.21

WEST ISLIP, N.Y., Nov. 29, 2021 /PRNewswire-PRWeb/ -- Skin tags are very common. Researchers estimate that about half of all adults will have at least one in their lifetime, with their incidence increasing after age 50. "Skin tags are almost always harmless," says Angie Seelal of Advanced Dermatology, P.C. "and do not require treatment. Removal is generally for cosmetic reasons or if they become irritated. Your doctor has several options for removing them but removal at home risks bleeding or infection and is not recommended."

What is a skin tag?

A skin tag, also known as an Acrochordon, is a small benign growth usually attached to the skin by a tiny stalk. It is composed of blood vessels and collagen and enclosed by an outer layer of skin. A skin tag hangs off the skin by its stalk unlike moles and some other skin growths that lie flat against the skin. Most skin tags measure just a couple of millimeters but some may grow as large as 2 centimeters. Skin tags may appear anywhere on the body but are most common where the skin rubs against itself, such as in armpits, groin, neck, eyelids, and under the breasts.

What causes skin tags?

A definitive cause of skin tags isn't known but because they show up in where the skin folds or wrinkles, it is thought that friction may play a role. Various studies have shown an association between skin tags and the human papillomavirus (HPV) and also a possible link to insulin resistance and high body mass index. Skin tags occur commonly in pregnancy, possibly due to hormonal changes and weight gain. There may be a genetic tendency to develop skin tags.

Who is at risk for skin tags?

Skin tags affect men and women equally. Based on the incidence of their occurrence and research studies, you may be more likely to develop skin tags if you are overweight or obese, have diabetes, are pregnant, or have close family members who have skin tags. "There is no sure-fire way to prevent skin tags," says Ms. Seelal, "but you might be able to minimize their occurrence by maintaining a healthy weight, getting plenty of exercise, and avoiding clothing or jewelry that repeatedly rub the same area."

How are skin tags removed?

Dermatologists are the best qualified medical professionals to remove skin tags. They have the training and skills to treat delicate areas, like the eyelid, to minimize scarring, and to diagnose growths that aren't skin tags. Removal methods include:

Your doctor will determine the best method based on the size and location of the tag and other factors in your medical profile. Treatment is typically done in the doctor's office and involves only mild, easily managed discomfort. There is seldom any permanent scarring. Skin tags do not grow back once removed.

"Skin tags shouldn't be a cause for concern," says Ms. Seelal. "They pose no threat to your health. You may never notice them and tiny ones might fall off on their own. If they are bothersome, either cosmetically, because they interfere with grooming activities like shaving, or because they are in a location that is prone to irritation, skip the do-it-yourself techniques and talk to a dermatological professional about the best way to remove them."

Bio: Angie Seelal, PA-C, is a Certified Physician Assistant through the National Commission of Certification of Physician Assistants.

Advanced Dermatology P.C. and the Center for Laser and Cosmetic Surgery (New York & New Jersey) is one of the leading dermatology centers in the nation, offering highly experienced physicians in the fields of cosmetic and laser dermatology as well as plastic surgery and state-of-the-art medical technologies.

Media Contact

Melissa Chefec, MCPR, LLC, 203-968-6625,

SOURCE Advanced Dermatology PC

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Here are 20 Wasatch Front holiday art markets that offer locally made gifts and treats – Salt Lake Tribune11.30.21

Sarah May started weaving as a way to connect with her Indigenous roots.

Born in the United States after her family immigrated from El Salvador, she feels disconnected, having never set foot in her home country.

I dont know my people. I dont know my language. I dont know any of that stuff, May said. So that was why I started weaving; I felt a connection knowing that my ancestors in some way or another were weavers, were artists, and it was literally ingrained and woven into their lives.

Mays shop, Cyanoweave, combines her cyanotype photography with her weaved mandala wall hangings, and it will be part of a holiday artist pop-up market at Finch Lane Gallery from 4 p.m. to 8 p.m. on Tuesday, Dec. 14, in Salt Lake City.

Her cyanotypes look like watercolor paintings, with bright hues of blue contrasting with images in white, and often depict nature and foliage. Cyanotype is a form of alternative photography that uses light sensitive chemicals that can be applied to paper, wood and fabric. A light box can be used, but May uses the suns ultraviolet light to expose and bring images to the surface.

For Mays woven wall hangings, she starts with the shape of circles, which for her is symbolic of cycles and the earth. She also is drawn to bright colors of yarn, like oranges and yellows that remind her of mangoes and cream. She works by intuition, drawing inspiration from the color of the yarn she picks up at thrift stores and things she finds in nature, such as driftwood and branches.

(Julie Hirschi | Special to The Tribune ) Salt Lake City artist Sarah May, whose parents came to the United States from El Salvador, started weaving as a way to connect with her Indigenous roots. She will offer her work at multiple holiday art markets on the Wasatch Front in December.

In addition to the Finch Lane pop-up, May will be participating in Alta Community Enrichment (ACE) Holiday Art Market Dec. 9 to 11.

These little local markets bring the arts to the people. I feel like art is something that people feel is really inaccessible, like its something that belongs in a museum, said May. But art is really a part of our way of life and our Indigenous communities. Not only Indigenous to the Americas, but across Europe and Africa, pretty much the whole world. People were creating art as a way of life and to process emotions and tell their stories.

When the Salt Lake City Arts Council created its first holiday craft market, it was trying to fill a need. Now, with so many art and craft markets opening during the season, its leaders decided to do things a little differently this year.

Instead of one central marketplace with several artists, there will be 12 different artists and craftspeople individually highlighted at the gallery on different days.

Each artist can bring more work than they usually would, and people can interact with them about the process, said Claire Taylor, visual arts coordinator for the Salt Lake City Arts Council. She deliberately chose artists from different mediums in order to highlight their craftsmanship. Having the artist there, she said, makes it all the more possible for people to learn about what went into producing the artwork.

The artisan Pop-Up Shops will take place Tuesdays through Saturdays, Dec. 4 to 21, from 4 p.m. to 8 p.m., and Saturdays from 11 a.m. to 3 p.m., at The Finch Lane Gallery, 54 Finch Lane, Salt Lake City. A list of the artists and the days they will be featured can be found on at

Concurrently with the holiday pop-up shops, the council is also partnering this year with the Utah Division of Arts and Museums to host the Statewide Annual Exhibit. This exhibition is an annual art show that rotates between different media, with this years media being craft, photography, video and digital art.

The show is usually held at Rio Grande Depot, but due to ongoing construction after the Salt Lake Valleys 2020 earthquake, exhibitions have been postponed or moved elsewhere. There will be an opening reception for the exhibit on Dec. 3, tied in with the December gallery stroll from 6 p.m. to 9 p.m., and the first pop-up shop will follow the morning after, on Dec. 4 at 11 a.m. Masks are required for entry.

May will also have an art piece displayed in the statewide exhibition, a retablo, which means behind an altar, that incorporates one of her cyanotypes and is a representation of her family heritage and her journey exploring her identity.

Im hoping that the artists are able to make a lot of sales and also make connections. Often at markets, its not only the sales, but also creating a network that leads to other things, said Taylor.

Taylor said that many artists were hit particularly hard during the pandemic. Many venues, including the Finch Lane Gallery, had to cancel their holiday markets last year, which meant the loss of art shows that are a way to bolster artists economically.

And so Im especially hoping with the artists were highlighting, each individual artist, itll lead to more beyond just the pop-up shop, she said.

There are many local art markets to choose from this year. New ones are opening, such as a European-inspired Vintage & Craft Market complete with mulled wine and apple cider, to join recurring events like Craft Lake Citys third annual Holiday Market in Ogden and the Silly Holiday Bazaar in Park City and now in Sandy.

The Hive Market SLC An artisans pop-up market provides locally made goods for the holidays. Trolley Square, 602 S. 700 East, Salt Lake City, and a new location in the Outlets Park City mall, 6699 N. Landmark Dr., Park City. Mondays-Saturdays 10 a.m.9 pm. and Sundays 12-6 p.m. starting Black Friday weekend through Christmas. Free admission. Find details at The Hive Markets Instagram page, @thehivemarketslc.

Neighborhood Hive Pop-Up Market The Neighborhood Hive is based on a concept similar to Seattles Pike Place Market, with open shopping at owner-operated store fronts of small businesses such as Hello! Bulk Market and Olio Skin Care. The pop-up will be going through the holidays, every Saturday, 9 a.m.1 p.m. in the parking lot of The Neighborhood Hive, 2065 E. 2100 South., Salt Lake City. More info at

Salt & Honey Market Holiday Makers This seven-week holiday pop-up will be full of handcrafted, one-of-a-kind, unique gifts from the best of Utahs makers. At two locations, Salt & Honey Market, 926 E. 900 South, Salt Lake City, and Fashion Place mall, 6191 S. State St., Murray. Going on now until Jan. 2. Hours vary by location. Visit their instagram page @saltandhoneymarket for the most up-to-date information.

Winter Farmers Market The downtown indoor Winter Farmers Market will feature over 60 fresh food and craft vendors, selling locally grown produce, meat, eggs, cheese, baked goods, sauces, condiments, chocolate and unique holiday items. The Gateway, 400 W. 200 South, Salt Lake City; Saturdays, 10 a.m.2 p.m. through April. Free admission. More info at slc farmers

Winterfest Art Jubilee An assortment of affordable, unique, handmade items from artists and artisans from all over the state; with everything from watercolor and oil paintings to jewelry, pottery, fiber art pieces, and handmade books. Bountiful Davis Art Center, 90 N. Main St., Bountiful; Tuesday-Friday, 10 a.m.6 p.m and Saturday noon5 p.m., now through Dec. 23. Free admission. More info at

Christkindlmarkt SLC Inspired by German Christmas markets, Christkindlmarkt SLC offers a unique holiday shopping and cultural experience, food and festive holiday entertainment outside in wooden vendor booths. This Is the Place Heritage Park, 2601 E. Sunnyside Ave. Dec. 1-4, 11 a.m.8 p.m. Free admission. More info at

Simple Treasures Weber Holiday Boutique Over 130 local crafters offer unique handcrafted gifts, holiday and home decor, trendy boutique fashion and accessories, jewelry and neighbor gifts. Golden Spike Event Center (Weber Fairgrounds), 1000 N. 1200 West, Ogden; Dec. 1-3, 10 a.m.8 p.m. and Dec. 4, 10 a.m.6 p.m. Grand opening on Dec. 1, 8-10 a.m. $5 admission with treats and treasure hunts. General admission $1 at the door (12 and under free). More info at

Utah Art Market Connecting the community with local artists and artisans from all over Utah. Selling fine art, prints, jewelry, pottery, metal work, wood work and seasonal holiday gifts. 1400 S. Foothill Drive in Foothill Village (formerly Steinmart), Salt Lake City; Dec. 2-4 and Dec. 9-11, 10 a.m.7 p.m. Free admission. Find more information on Instagram page @utahartmarket.

Craft Lake City Holiday Market After a virtual marketplace last year, Craft Lake City will return to Ogdens Nine Rails Creative District for a two-day, in-person event that will feature handmade gifts by dozens of Utahs top artisans, vintage vendors and craft foodies. The Monarch, 451 25th St., Ogden. Dec. 3 from 5-10 p.m. and Dec. 4, 10 a.m.5 p.m. More info at

Finch Lane Pop-Up Shops The Salt Lake City Arts Council is partnering with the Utah Division of Arts and Museums to exhibit the Statewide Annual competition in Craft, Photography, Video and Digital. In conjunction with the exhibit, they are holding Finch Lane Pop-Up Shops by individual artists and craftspeople. Finch Lane Gallery, 54 S. Finch Lane (1340 East). Dec. 3Jan. 5. More info at Masks will be required for entry.

Silly Holiday Bazaar The Park Silly Market will have two locations of the Silly Holiday Bazaar this year featuring artists and crafters from Summit and Salt Lake counties. Free parking and photos with Santa. New location in The Shops at South Town, 10450 S. State Street. Dec. 3-4, 12-8 p.m.; Dec. 5, 12-6 p.m. DoubleTree Park City Yarrow, 1800 Park Avenue, Park City. Dec. 10, 5-9 p.m.; Dec. 11-12, 10 a.m.5 p.m. Free admission. More info at

Provo Downtown Holiday Market Featuring vendors with local crafts, food, music, an ice sculpture, Santa and Lights On, a tree and park lighting ceremony at 5:30 p.m. Pioneer Park, 500 W. Center St., Provo; Dec. 4, 4-8 p.m. Free admission. More info at Provo Recreations Facebook page.

Red Butte Garden Holiday Open House & Art Fair Local artists will bring an array of handmade gifts, including jewelry, glass art, pottery, fiber art, wearable art, natural soaps and lotions. Red Butte Garden Orangerie, 300 Wakara Way. Dec. 4-5, 10 a.m.5 p.m. Free admission. More info at

Utah Museum of Fine Arts Holiday Market The UMFA annual Holiday Market will feature local artists such as glass artist Anthony Barbano, painter and muralist Traci OVery Covey. Find handmade creations in glass, ceramics, paintings, jewelry, photography and artisan chocolates. Due to ongoing COVID precautions, attendees are asked to register in advance at Admission to the market is free with reservation, but the museum gallery itself requires an entrance fee. Marcia and John Price Museum Building, 410 Campus Center Drive. Dec. 45, 9 a.m.5 p.m. More info at

Vintage & Craft Holiday Market Inspired by European holiday markets, Preservation Utah will be holding its first annual holiday market complete with Glhwein (mulled wine) and apple cider. Featuring local artists selling vintage and traditional crafts. At the Memorial House in Memory Grove Park, 375 N. Canyon Rd. Saturday, Dec. 4, 10 a.m.6 p.m. More info at

Penny Lane Holiday Market A pop-up market featuring local vendors selling handmade goods, treats, art, vintage and gift items. Crescent Hall, 11020 S. State St., Sandy. Dec. 6-8, 10 a.m.8 p.m. Visit for more info.

Alta Community Enrichment (ACE) Holiday Art Market Featuring handmade holiday gifts from a number of local artists. Our Lady of the Snows, 10189 East Highway 210, Alta. Dec. 9-11, 2 - 7 p.m. Attendees will need to show proof of being vaccinated or show proof of a negative test. More info at

Art Haus Christmas Market Enjoy a night at Art Haus, a pottery, drawing and painting studio. Come meet the makers, buy crafted handmade gifts for the holidays, enjoy music, snacks and drinks. All of the makers are students and instructors of the studio. 177 E. 900 S. Suite G, Salt Lake City. Dec. 11, 4-8:30 p.m. RSVP on the website

Holiday Urban Flea Market The flea market features eclectic vintage and antique items, clothing, records, furniture, art and handcrafted items. The Gateway, 18 North Rio Grande St. Sunday, Dec. 12, 10 a.m.4 p.m. Admission $2; children 12 and under free. More info at

Virtual Hanukkah Market Due to COVID-19, the I.J. & Jeann Wagner Jewish Community Center will once again have its traditional Hanukkah market online. Starting in December, shop its website for Hanukkah essentials, holiday gifts and books from The Kings English Bookshop. More info at

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New nanochip reprograms cells in the body to perform different functions – New Atlas11.30.21

A team of researchers led by Chandan Sen at the Indiana University School of Medicine, is moving a new nanochip device, which can reprogram skin cells in the body to become new blood vessels and nerve cells, out of the prototype phase.

One of the more remarkable medical developments in the past two decades has been the ability to take specialized adult cells and revert them into the kind of non-specialized stem cells found in embryonic tissue. These stem cells have great therapeutic potential because they can then be induced to grow into various cells, tissues, and (eventually) organs that will be completely compatible with the patient, eliminating the problem of tissue rejection or finding donors.

Unfortunately, doing this requires complicated laboratory procedures, and, along with many alternatives, can raise certain risks, including giving rise to cancerous cells. Instead, a simpler system is needed that does not require the elaborate steps that stem cell perversion requires.

The IU team's approach is to forgo the laboratory and turn the human body into its own cell programmer using a technology called tissue nano-transfection. This uses a silicon nanochip that has been printed to include channels ending in an array of micro-needles. On top of the chip is a rectangular cargo container, which holds specific genes.

Indiana University

Propelled by a focused electric charge, these genes are introduced to the desired depth in the living tissue and alter the cells, converting the location into a little bioreactor that reprograms the cells to become different kinds of cells or multicellular structures, such as blood vessels or nerves, without the need for elaborate laboratory techniques or hazardous virus transfer systems. Once produced, these cells and tissues can help to repair damage both locally or in other parts of the body, including in the brain.

"This small silicon chip enables nanotechnology that can change the function of living body parts," says Sen, director of the Indiana Center for Regenerative Medicine and Engineering. "For example, if someone's blood vessels were damaged because of a traffic accident and they need blood supply, we can't rely on the pre-existing blood vessel anymore because that is crushed, but we can convert the skin tissue into blood vessels and rescue the limb at risk."

Indiana University

The technology has been under development for over five years, and the IU team is now focusing on going beyond prototyping to making the nanochip a practical concern that can be used in clinical settings. This includes securing US FDA approval next year, which would open up the potential for clinical research in people. Potential applications in civilian and military medicine include repairing brain damage resulting from a stroke or reversing nerve damage caused by diabetes.

"This is about the engineering and manufacturing of the chip," says Sen. "The chip's nanofabrication process typically takes five to six days and, with the help of this report, can be achieved by anyone skilled in the art."

The research was published in Nature Protocols, and the video below explains the nanochip's basic technology.

Source: Indiana University

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Why The Piolet D’Or is Climbing’s Biggest and Most Debated Award – The New York Times11.30.21

Garibotti knows the danger firsthand. By his tally, more than 30 people he has roped up with have later died climbing. The Piolets dOr twice tried to nominate Garibotti for the award, once in 2006, for a new route on Cerro Torre, in Patagonia, and once in 2009, for the first traverse of the entire Cerro Torre massif. Twice he refused.

Most shocking was whom the jury decided to honor in 1998: a Russian team that made the first ascent of the west face of the Himalayan peak Makalu in 1997. Two of the climbers on the expedition died in the process. The organizers introduced a new criterion after backlash that year, requiring, according to Trommsdorff, that you have to come back in one piece.

The problem, in Garibottis opinion, isnt that the awards encourage climbers to take more risk, but that in awarding risky climbs, they validate risky behavior. If you have representation of climbs that are reckless, there are going to be more reckless climbs, he said.

After winning a Piolet dOr in 2019 with his Slovene teammates Ales Cesen and Luka Strazar, the British climber Tom Livingstone wrote in an essay on his website that the award plays on my human ego in worrisome ways.

I already have a devil on my shoulder at the end of a run-out a section of sparsely protected climbing that can result in dangerous falls who whispers, uh oh, youre gonna take a big one! Livingstone wrote. I dont want another offering me a golden trophy. He accepted the award only because his teammates wanted to.

Of course, for many climbers, danger is a big part of the sports appeal.

We have to recognize that in traditional mountaineering, death is a possibility, said Reinhold Messner, 77, one of the most lauded alpinists of the last century. If its not a possibility, its not mountaineering. The art of surviving is just that. Its an art.

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Eight small businesses in Worcester reflect on importance of Small Business Saturday – Worcester Telegram11.30.21

WORCESTER Central Massachusetts is home to many iconic manufacturers: Polar Beverages, Table Talk Pies, Riverdale Mills, Fulcrum Acoustics.Look a little closer and you'll find small businesses across the region showing their own ingenuity and creativityright next door.

Small Business Saturday, founded by American Express in 2018 to give customers who shop at small businesses a discount on their AmEx cards, has become a nationwide event to supportsmall shops across the country. In Worcester, small businesses benefit from the event as both dedicated customers and curious neighbors go out to shop that day.

Small Business Saturday fallson Nov.27 this year, and these eight Worcester businesses shed light on how the event gives them a boost before the holiday season, which for many is their busiest time of year.

Founded in 1852 and billing itself as the oldest art store in the U.S., CC Lowell goes beyond the classic art store, selling art supplies along with the work of local artists. Its weekly Mini Merry Market, an extension of its summer market, features tables where artists set up shop for the afternoon to sell their work, fromhand-sewn baby bandanas, block-printed shirts,stickers, yarn and linocut prints.

AmandaSanterre, a manager at CC Lowell, said this is the store'sfirst year doing the markets, which have been a success. Santerre said shesells her linocut prints at the markets, as well as online on Etsy and other markets in the area.

"We go real hard on Small Business Saturday," she said with a laugh."Were going to have a market that day, and that weekend kicks off our three-day market starting Friday. Well definitely have some large sales that are still a secret, so youll have to stay tuned on our social media to find out about them for Small Business Saturday. Well have store sales and artists selling stuff here, and we always do fun stuff that day."

CC Lowell will extendits hours for the occasion, open from 10 a.m. to7 p.m.More customers come into the store that day, Santerre said, eager to showtheir support.

"I think we have a really great customer base that cares about shopping local and supporting us, so we always see a ton of people, with lots of regulars and lots of new people too," she said.

Located in the Worcester Public Market, K Sense is the handmade candle company run byKatherine Aguilar. Aguilar started making candles in thesummer of 2019, giving extra character to her candles by upcycling oldliquor, soda and winebottles to fill with her all-natural soy candle wax.

Aguilar sells her candles both in-store, online and at community pop-ups, such as onerecentlyat Redemption Rock Brewing Co.

RunningK Sense with two employees, shesaid she's excited for this year's Small Business Saturday.

"I've only been in one Small Business Saturday," Aguilarsaid, which was last year during the pandemic."Im hoping this year itll be a very high sales day."

In addition to her candles, Aguilar sells thework of other local women who hand-make products in her store, from greeting cards, stickers andtote bags to a line of"doggie skin care," including shampoo and sunscreen for dogs.

All the products in her store are sustainable, plastic-free and woman-made, Aguilar said.

Across from K Sense in the Worcester Public Market is Girly Girl Soap, the soap shopofMichele Montalvo.

Workingfull time in human resourcesat UMass Memorial Medical Center, Montalvo said she found a passion for making her own soapsas a hobby in 2018, when shebegan selling her products online and atmarkets on weekends.

Montalvo said she decided to make vegan and plant-based products,all phthalate-free,using ingredients she trusted, such as essential plantoils and coconut milk.

"I was looking for something to fill my time with after I got my master'sdegree, and I just started making soap," Montalvo said."I loved it. In 2018 I decided it was something I wanted to build into a business.I was trying to be conscious of what I was putting on my skin and in my body when I started making soapbecause everything that goes on your skin goes into your body."

Beyond 40 different types of soap, Montalvo learned how to makeshampoo and conditioner bars, facial bars, scrubs, body butter balm, lip balm andbody oils.

Although her customer base is mostly female, Montalvo said she also sells her products to men who swear by herproductssuch as her facial bars, which one customer said cleared his skin.

Montalvo said she makes her products at home and has one employee who helps sell her products at the WPM.

While many of the items in Seed To Stem are handmade,co-owner Virginia Orlando saidabout 20% of products in the shop are made by her and Seed To Stem's six employees including theirterrariums and container gardens.

"We just try to make sure the shop is full," Orlando said. "We do a lot of planting and making of terrariums ourselves, which we sell a lot of during the holidays, so we really try to make sure were fully stocked and ready."

Most products at the shop arepopular during the holiday season, she said, mentioning handmadeornaments, holiday soy candles,crystals and plants.

Small Business Saturdaybrings more crowds out to shop small, Orlando said,highlighting the importance of the event for shops like hers that might be overlooked.

"Were thankful for Small Business Saturday," she said."The big-box stores have had Black Friday for so long, so it's nice to see small business can be celebrated and give us a little extra boost before the start of the busy holiday season."

Comic book store That's Entertainment has been a Worcester staple for 41 years, specializing in not only back-issue comics but also vintage and used video games and consoles,board games, role-playing games, puzzles, gift itemsand toys.

Sorana Gatej, the store'smarketing manager, said comics are the store's most popular item, but the customer base shows a consistent interest in the video games and card games such as Pokemon and Magic: the Gathering.

The store supports local comic artists and writers with a featured local creators section. Gatej said among the comic inventory are books by local artists Andy and Veronica Fish, Derek Rook andHans Rickheit, along with longtime That's EntertainmentcustomersChristos Gage, Brian Nelson andChris Denmead.

Besides comics, games sold in-store include Star Realms, a game developed byFramingham-based Wise Wizard Games, which Gatej said sells regularly.

Gatej said Small Business Saturdayhelps the business, especially since customers are dedicated and supportive of the Worcester comic store. She said she feels fortunate that people care so much about keeping That's Entertainment around.

"Theyll tell us, I would rather support you than a big-box store and I really want to keep you guys around, so they choose to shop here," she said.

"Theyre strong supporters and were really grateful for that.I guess were doing something right," Gatej said with alaugh.

Leatherwork is featured at Alan James Co. in the Worcester Public Market.

Don't go into the store asking for Alan the shop owner is Bill Laudon, who turned his hobby of craftsmanship into a full-time job.

Laudon said he got his start inarchitectural sheet metal, "wrappingmansions in copper" he said. After learning the fundamentals of metalwork four years ago,Laudonstarted working in the workshop at Wellesley College, experimenting in making knives.

"Put me in a workshop and while everyone is eating lunch I'll be making something," he said."I was making knives at one point which I really love and I needed to make a sheath. So after my third knife I looked into the roots of making a knife sheath, and four years ago I made my first one, my first experience with leather."

So far Laudon has experienced one Small Business Saturday since opening his shop last year, one month before the onset of the pandemic. He hopes for a successful day during the event this year, saying with a chuckle, "Small Business Saturday should be every other Saturday."

People appreciate small business in Worcester, Laudon said, which he saidbenefits everyone from customers to creators.

"These little events are something I have to lean into and hope for to keep myselfgoing," he said.

Laudon said he wanted a brick-and-mortar place to grow his craft. Hemakes his leatherwork in his storefront, specializing in no certain product but making wallets, purses, leather bowties,briefcases, belts, pouches, umbrellas and custom items.He said there is no limit outside his own imagination.

"I dont necessarily have a product or line of products," he said."What I offer here is a way to experience a lost art thats not been viewed for so long. This art form has been dominated by a luxury industry and controlled in a way and not many for quite some time have been able to experience it, so I thought this would be a fantastic way to fill that gap I see."

While Worcester brewery Redemption Rock won't be having any special sales of its own on Small Business Saturday, it'll be hosting itsthird annual Holiday Gift Market. Sixteen local small artisan craft makers will be at the event selling their work from 11 a.m. to 3 p.m., where customers can come shop while enjoying Redemption's craft beer.

"As a small community-focused and locally-focused business, getting the support of the community is essential to our business and it's also personally what we like to do," Redemptionco-founder Dan Carlsonsaid. "We like to get out there and support other small businesses in our community as well, so having a big day dedicated to that is a lot of fun."

Redemption Rock opened three years ago andhas eight full-timeemployeesincluding its four owners.The brewery hasa taproom and cafe serving beer, coffee, snacks and charcuterie.

Carlson said even without the brewery participating in Small Business Saturday with its own sales,the holiday market will benefit both Redemption and the vendors selling their work.

"Hopefully it'll draw people to come out and support these small businessesand it'll obviously benefit us, but then it's also a way for us to support thesebusinesses that are even smaller than we are," he said.

Carlson said Worcester is a small business-oriented city.

"I think it's verypassionate about the local community, whether it's retail or restaurants. People love supporting these smaller, cool, organic businesses that add to the personality of the city."

Opened in 2013, Birch Alley is a curated boutique shop run by fourwomen in the Crompton Collective.

While the shop does not make its own products, it has featuredthe work of a plethoraoflocal creators over the yearslikeVonnie Williams, Vertigo,Olive & Co. Paper,Little Man OriginalsandBirch MountainPottery, co-owner Virginia Orlando said.

"I think theres a little something for everyone in the shop," she said. "We have jewelry, soaps for men, Father's Day and Mother's Day things, robes and kimonos for women, and stuff for the kitchen, bedroom and open house decor."

Orlando said Christmas is Birch Alley's busiest holiday, during which they make a majority of their annual sales, butSmall Business Saturday is a staple event for the shop as well.

"Small Business Saturday is usually pretty busy," she said. "Its well publicized, so well do something for it but were all-in for our Christmas Day right now because its so much work to get that going. Its usually a big to-do."

Birch Alley organizes a raffle for customersto support a local charitable organization. Orlando said in the past the shop raised money for a veterans' organization and this year will be giving proceeds and donations toPawfect Life Rescue in Uxbridge. The customer who wins the raffle receives a Birch Alley holidaygift basket.

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The Ellison’s is so good it couldn’t wait for the hotel to open – Oklahoman.com11.30.21

The 405 diningscape received its first gift of the holiday seasonbefore Black Friday with the arrival of Milo, the restaurant anchoring The Ellison Hotel.

The new boutique hotel won't open until Dec. 6, but Milo is open for lunch and dinner.

Milo issetwest of the stunning lobby at the entrance of The Ellison. Earth tones abound in the library-flavored,38-seat dining room featuringreeded glass cabinets, and an L-shaped bar tucked into a wood-paneled corner all lit by low-hanging fixtures shaped like globes and half-moons.

The kitchen boastsa culinary supergroup executive produced by localrestaurateur and consultantChris Lower. The co-founder of The Metro Wine Bar and Bistro, Big Truck Tacos, Pizzeria Gusto and Back Door BBQ, brought together chefs Joshua Valentine, andJoseph Royer (Saturn Grill to collaborate withfood and beverage director Michael OHara (Vast) to seed Milo.

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The result is an eclectic menu reflecting global inspiration but rooted in Oklahoma.

Executive chef Valentine's opening menu fuses French technique with flavors and tradition from the Deep South and Southwest. Dishes straight from the former Top Chef contestant's wheelhouse like Buttermilk-Fried Quail with mashed potatoes, smashed potatoes and collard greens. (That Chorizo gravy, tho!)

But we're getting ahead of ourselves.

Before getting to entrees, Milo offers the kind of warm, inviting atmosphere that begs for cocktails andhors d'oeuvres. Luckily, Milo boasts one of the city's top-class bar managers and drink-techniciansin O'Hara. And then there's Valentine and his propensity for delivering toe-curling flavors usually under the influence of pork.

The Crispy Pork Rillettes arrive underchow chow and shouldered into course-grain mustard. Plates returning as clean as these will surely confusethe dishwasher.

But I imagine the oozy Pimento Cheese Arancini will be a crowd-pleaser. The risotto fritter comes with a green tomato chutney. It's like nachos and hushpuppies ran off to a secret cottage in the apple orchard to, umm, cook.

The Blue Corn Tamale Tart offers a rare treat in that it features garlic custard. Savory custards are a lost art Milo appears to have borne again. Smoked trout and tomato preserves join the party going on in the porky blue corn tart.

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Not far away are the Milo Sopes, which are blue-corn tarts topped with black bean puree and green pico to join three optionalspicy blends for carnivores and herbivores. Ignore the bison picadillo at your own peril.

From the middle of the menu, we tried a salad and some pasta.

TheThree Sisters Salad (seasonal squash, black-eyed peas and corn) is served beneath a tomato vinaigrette and farmer's cheese. Payinghomage to Oklahoma's tribal roots, the salad delivers a variety of textures and well-balanced garden-fresh flavor.

Gastronauts will appreciate the Apple Agnolotti served with chicken liver mousse, apple, and crispy chicken skin over a sage brown butter. The result isrollercoaster of sweet and savory texture-swapping that will have some screaming for more and frighten others.

(Pro tip: If you're among the frightened, send me the doggy bag.)

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Did I mention there was Buttermilk Fried Quail with Chorizo Gravy? If you have questions, the answer is almost certainly yes.

The entreesmenualso features a grilled tenderloin, roasted local chicken, and seared striped bass. Vegetarians will appreciate the Black-Eyed Pea Falafel with tomato fondue, cashew lemon cream and wild grain pilaf.

During a preview service, we also tried the other vegetarian option,Ricotta Dumplings. It's a play on classic gnudi with roasted squash, corn, roasted peppers and corn cream. It's really hard to find fault in cheese dumplings towing this kind of payload.

Finally, there was the Pork Adovada. Valentine has presented anopulent interpretation of classic New Mexican cuisine by way of traditional adobada from southwestern Mexico. The challenge of the dish for restaurants is making fast a dish that takes a long time to make.

The rich red chile sauce is integral because that's usually what chunks of pork braise in to find their spicy flavor and fork tenderness.

It takes hours.

Milo deliverslush, thick cutletsof fork-tender mid-rare tenderloin in a pool of velveteen red chile beached against creamy polenta and three-sister hash. This one showed signs of transcendence if we can just figure out a way not to leave a trace of that sauce on the plate.

Pastry chef Kaci Messerly's buttermilk panna cotta was a reminder of how good custard is when it's not vanilla pudding. Look forward to seeing what she as to offer under less bacchanalian circumstances.

When the hotel opensbreakfast service will be served 6:30to11 a.m. Monday through Friday and7 to10 a.m. Saturday and Sunday. Reservations are now available for lunch and dinner 11 a.m. to 2 p.m. Monday through Friday, with brunch 10 a.m. to 2 p.m. on weekends. Dinner is served 5 to 10 p.m.

Small bites are served 2 to 5 p.m. and 10 p.m. to midnight daily. The bar is open 10 a.m. to midnight daily.

For more information, call 463-0055.

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